Van de Ven Double Ends The Toffees' Unbeaten Streak at New Stadium
The Dutch defender emerged as the initial backline player to net twice in a English top-flight match for Spurs since Jan Vertonghen in March 2013.
Key points
The Spurs defender heads home twice in first half
Everton's defender has goal disallowed after video check
Pape Matar Sarr nets third in dying moments
The defeat is Everton's initial at their new ground
Micky van de Ven found the net twice as Tottenham extended their winning streak in away games in the top division and handed the Toffees their initial loss at Hill Dickinson Stadium.
Everton were unbeaten in their last five matches at their new ground at the dockside location, having left their historic home behind after 133 years at the end of last season.
But Tottenham's leader Van de Ven pounced on two occasions from corners in the opening 45 minutes to place their impressive record at jeopardy, and they were unable to mount a comeback before the midfielder - set up by ex-Everton forward Richarlison - headed home a final goal to seal the victory.
The Everton defender thought he had equalized the tally a short while after the defender's first goal, glancing a bullet header past the Spurs keeper from an Everton corner.
Beto, meanwhile, missed a number of chances, while Vicario made a succession of fine stops to guarantee Tottenham went five away games without defeat in the English top flight.
But the VAR intervened, instructing Craig Pawson to check the goal on the pitchside monitor and the official ruled that Jack Grealish and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
The win elevates the manager's side into third place in the division, five points off north London rivals and table-toppers the Gunners.
The Merseyside club remain in 14th position and are half a dozen points ahead of the relegation zone.
Tottenham analysis: Van de Ven excels in duties at both ends of pitch
After a uninspiring weekday performance in the Champions League against the French side, where they mustered a mere two shots on goal, Frank opted for Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.
The new arrival was unable to make much of an impact before being replaced for the substitute after 60 minutes on the field, but it emerged he wasn't needed in the final outcome.
Centre-back Van de Ven converted into an offensive threat to be feared.
Spurs' opening strike came from a cleverly executed set-piece play, with Rodrigo Bentancur directing the ball back across the six-yard box for an unmarked the defender to score.
And the captain - filling in as skipper in Cristian Romero's unavailability - notched his second in added time as he rose above Jordan Pickford to nod in.
Van de Ven was just as outstanding in defensive duties, combining well with his defensive colleague as the pair dealt superbly with the 34 crosses sent their way by Everton.
Toffees breakdown: Toffees missing finishing touch
The club's new home had been a fortress, but it appears the novelty may have faded slightly and fans flocked to the exits after the midfielder's final goal for Tottenham.
The end in the team's unbeaten home run will not be a major worry for the manager, but their attacking woes will be.
The forward and Thierno Barry - the Everton's pair of established strikers - had netted only a single goal combined before Sunday's outing.
And they were unable to add to that poor tally on a damp and dreary evening on Merseyside.
Beto's performance was summed up when he opted to overhead kick a clear chance from close range, even with having room and time to readjust for a more conventional shot that would have challenged the keeper.
Barry, too, failed to make an impact after coming on for Beto in the second half.
It was not for a shortage of opportunity. The majority of the home side's attacks came through the winger and Ndiaye, who tirelessly whipped threatening crosses into the Spurs box.
What next for both teams?
The Toffees: Moyes' men travel to the Stadium of Light in the Premier League on Monday, 3 November at 20:00 GMT.
Spurs: The London club travel to Newcastle's ground on late October for their next round League Cup tie against the Magpies.